临床综合征与MCM8和MCM9的双性生殖系变异相关

Noah C Helderman1, Ting Yang2, Claire Palles3

  • 1Department of Clinical Genetics, Leiden University Medical Center, Leiden, the Netherlands.

HGG advances
|July 20, 2025
PubMed
概括

在MCM9中双变异与多重症,胃癌和早期结直肠癌 (CRC) 有关. 两种MCM8和MCM9变种都与阴性腺和早期生殖细胞瘤有关,建议将其纳入遗传检测和监测.

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