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根据胚胎移植日期的不同妊娠期的IVF胚胎和妊娠囊大小的变化

Sughashini Murugesu¹, Amy Shearer², Kristofer Linton-Reid³

¹Queen Charlotte's and Chelsea Hospital, Imperial College, London W12 0HS, UK.; Department of Metabolism, Digestion and Reproduction, Imperial College, London, UK..

Reproductive biomedicine online

|July 20, 2025

概括

在试管婴儿怀孕中,胚胎和妊娠囊的大小各不相同. 47天或更晚的胚胎移植日期空的妊娠囊准确预测流产,可能允许更早的诊断.

科学领域:

生殖内分泌学生殖内分泌学
临床胚胎学临床胚胎学
产科和妇科产科和妇科

背景情况:

在体外受精 (IVF) 周期中存在胚胎和妊娠囊大小的变化.
在怀孕早期,确定绝对流产诊断可能具有挑战性.

研究的目的:

调查胚胎和妊娠囊大小是否在特定的妊娠年龄不同,根据IVF胚胎移植日期.
评估胚胎移植日期是否可以帮助最终诊断流产.

主要方法:

对1161个试管婴儿胚胎移植 (2019-2021) 的回顾性队列研究.
收集的数据包括胚胎移植日期,胚胎年龄,冠长度 (CRL) 和平均囊径 (MSD).
怀孕活力在11-14周时进行评估.

主要成果:

根据胚胎移植日期在特定妊娠年龄观察到的CRL和MSD的显著变化.
在胚胎移植日期怀孕47天或更长时间的空妊娠囊显示出100%的流产预测值.
包括1161例试管婴儿移植;76.8%的可活性,23.2%的不可活性在11-14周.

结论:

胚胎和妊娠囊的尺寸因胚胎转移日期而有显著的变化,对于给定的妊娠年龄.
在胚胎移植日期按妊娠47天的空妊娠囊是流产的明确指标.
这一发现可能使得在试管婴儿怀孕中更早地确立绝对流产诊断.

关键词:

胚胎转移是胚胎的转移.在这个过程中,IVF IVF.流产流产流产流产的诊断流产的诊断

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In Vitro Fertilization

In Vitro Fertilization

In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
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