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作为Aβ聚合抑制剂的短的合成和机制研究

Rajesh Parmar1, Naina Sehra1, Indresh K Maurya2

  • 1Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S. A. S. Nagar, Punjab 160 062, India.

Bioorganic chemistry
|July 20, 2025
PubMed
概括

一个新片段有效地抑制了粉样β (Aβ) 聚合,这是阿尔茨海默病 (AD) 的关键过程. 这种酸在低度下表现出显著的抗聚合作用,为AD提供了潜在的治疗策略.

关键词:
阿尔茨海默氏症的疾病是阿尔茨海默氏症.粉样蛋白-β聚合的聚合.生态友好型合成方法迷你类的微型.神经毒性 神经毒性

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