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全球流行病学和间歇性肺病的负担

Paolo Spagnolo¹, Sabina A Guler², Nazia Chaudhuri³

¹Respiratory Disease Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, Padova, Italy.

The Lancet. Respiratory medicine

|July 20, 2025

概括

由于数据不一致,确定间歇性肺病 (ILD) 的全球负担具有挑战性. 然而,研究表明,全球ILD的发病率和流行率正在上升,需要进一步的流行病学研究.

科学领域:

肺部医学肺部医学
流行病学流行病学
公共卫生公共卫生

背景情况:

全球间歇性肺病 (ILD) 的发病率和患病率很难确定,原因是罕见,报告不一致,以及不同的风险因素.
尽管存在挑战,但研究表明,随着时间的推移,ILD发病率和流行率的趋势在不断增长.
存在显著的地理差异,特别是连接组织疾病相关的ILD和过敏性肺炎.

研究的目的:

审查有关ILD流行病学和负担的当前文献.
确定知识缺口和需要在ILD流行病学方面进行进一步研究的领域.
突出医疗保健准入和社会经济因素对ILD结果的影响.

主要方法:

关于ILD流行病学的最新文献的非系统审查.
对影响ILD发病率,流行率和地理分布的因素的分析.
检查影响ILD的医疗保健准入和社会经济差异.

主要成果:

异常性肺纤维化是最常见的ILD;其他如结缔组织疾病相关的ILD和过敏性肺炎显示地理变异性.
关于许多ILD的数据仍然很少,在医疗保健获取方面存在很大的差异,特别是在低收入和中等收入国家.
社会经济不平等明显影响ILD的发病率和死亡率.

结论:

进一步的流行病学研究至关重要,以了解日益增加的ILD负担.
健康数据库和污染监测等新工具为ILD研究提供了有前途的途径.
了解遗传和环境因素的相互作用是解决ILD日益增长的挑战的关键.

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