糖尿病手部并发症在糖尿病前期:一个受控的观察性研究
Kemal Erol1, Ezgi Akyıldız Tezcan2, Ulaş Serkan Topaloğlu3
1Division of Rheumatology, Department of Physical Medicine and Rehabilitation, Selcuk University Medical Faculty, Konya, Turkey.
糖尿病前期与手部功能不佳和更多的并发症有关,例如关节运动受限. 手腕道综合征和触发指显著导致糖尿病前期患者的手部功能障碍.
科学领域:
- 内分泌学 在内分泌学.
- 类风湿病学 类风湿病学
- 肌肉骨健康 肌肉骨健康
背景情况:
- 糖尿病前期,一种高血糖的状态,是一个日益严重的全球健康问题.
- 早期发现糖尿病前期并发症对于及时干预至关重要.
- 手部并发症和功能缺陷在代谢障碍中越来越多地被认可.
研究的目的:
- 评估糖尿病前期患者手部功能和糖尿病手部并发症的患病率.
- 为了确定与糖尿病前期手部功能障碍相关的因素.
- 为了探索糖尿病前期对手部早期肌肉骨的影响.
主要方法:
- 一项受控的观察性研究,涉及100名糖尿病前期患者和50名对照人群 (18-65岁).
- 使用Duruöz手指数 (DHI) 评估手部功能;用数字动力表测量握力.
- 手掌道综合征 (CTS),关节运动受限 (LJM),触手指 (TF) 和其他临床评估的手部疾病的流行.
主要成果:
- 糖尿病前患者的手部功能明显受损 (较高的DHI分数,P=.025).
- 在糖尿病前组中,受限关节运动 (LJM) 更为普遍 (P=.024).
- 手道综合征 (CTS),触发指 (TF) 和握力降低与手部功能受损显著相关 (分别P=.002,P=.007,P=.003).
结论:
- 糖尿病前期与手部功能减弱和手部并发症增加有关,特别是LJM.
- 管综合征 (CTS) 和触发指 (TF) 与糖尿病前期手部功能障碍有着密切联系.
- 像HbA1c这样的血糖标记在这个队列中没有与手部功能障碍直接相关.
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