一个患者的欧性胃肠炎和欧性皮肤炎:同一枚硬币的两面?
Leilynaz Malekafzali1, Bibi Naghibi Torbati2, Fahd Jowhari3
1Family Medicine, University of Toronto, Toronto, Ontario, Canada.
BMJ case reports
|July 20, 2025
概括
乙酸性胃肠炎 (EGE) 和乙酸性皮肤炎可以同时发生,表现为腹痛和皮疹. 用口服普得尼松和质子抑制剂 (PPI) 及时治疗有效地解决了60多岁的女性患者的症状.
科学领域:
- 胃肠病学 胃肠病学
- 皮肤病学 皮肤病学
- 免疫学 免疫学 免疫学
背景情况:
- 生性胃肠炎 (EGE) 是一种罕见的疾病,其特点是胃肠道的生性透.
- EGE与乙酸性皮肤炎的同时发生并不常见,这给诊断带来了挑战.
- 低甘球蛋白血症和蛋白质丧失肠病也可能是相关的疾病.
研究的目的:
- 报告一种共存的eosinophilic胃肠炎和eosinophilic皮肤炎的情况.
- 在这种情况下,要突出诊断方法和治疗结果.
主要方法:
- 一名女性患者的临床表现,出现了反复出现的胃上疼痛,恶心,吐和皮疹.
- 诊断工作包括身体检查,实验室研究 (外周血液叶绿素,低albuminemia),胃镜用活检和皮肤活检.
- 治疗开始使用口服普雷迪尼松和质子抑制剂 (PPI).
主要成果:
- 胃镜检查和活检证实了前肠 (EGE) 中埃索诺菲尔透的增加.
- 皮肤活检显示,皮肤中存在埃索诺菲尔透,与埃索诺菲尔皮肤炎一致.
- 腹部症状在治疗开始后48小时内消失.
- 随访胃镜显示了显著的粘膜和组织学改善,随后出现皮疹.
结论:
- 乙酸性胃肠炎和乙酸性皮肤炎可以同时出现.
- 皮质类固醇和PPI的组合可以成为这种情况的有效治疗策略.
- 早期诊断和及时管理对于有利的结果至关重要.
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