前列腺癌倾向风险调整预防的心理社会结果:纵向观测混合方法研究的研究方案
Maike K Klett1,2, Peter Albers2,3,4, Jale Lakes2,3
1Clinical Institute of Psychosomatic Medicine and Psychotherapy, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany maikekim.klett@med.uni-duesseldorf.de.
BMJ open
|July 20, 2025
概括
这项研究评估了一个新的前列腺癌 (PCa) 预防诊所对高危人群的心理社会影响. 它旨在了解焦虑,风险感知和参与家庭PCa预防策略中的障碍.
科学领域:
- 在瘤学瘤学.
- 心理学 心理学 心理学
- 预防医学 预防医学
背景情况:
- 前列腺癌 (PCa) 是全球男性的主要癌症,遗传和家族史是显著的风险因素.
- 增加PCa风险与增加PCa特定的焦虑和痛苦有关.
- 对于家族性或遗传性PCa倾向的现有预防策略是有限的,需要研究其心理影响.
研究的目的:
- 评估参与新型"ProFam-风险"预防诊所的男性的纵向心理社会轨迹.
- 评估PCa特异性焦虑,感知风险和PCa家族或遗传倾向的个体的个人控制.
- 确定参与风险适应性PCa预防的促进者和障碍者.
主要方法:
- 一个纵向观察混合方法设计,比较预防诊所中的病例组 (CAG) 与泌尿病患者的控制组 (COG).
- 心理社会结果,包括PCa特异性焦虑 (前列腺癌纪念焦虑问卷),将在多个时间点进行评估.
- 来自半结构面试的定性数据将使用定性内容分析来分析,以探索参与促进者和障碍.
主要成果:
- 主要终点是病例组中PCa特异性焦虑的纵向过程.
- 二级终点包括对病例和对照组之间的心理社会结果的比较以及病例组内感知风险和控制的变化.
- 定性访谈将提供对参与者经验的深入理解.
结论:
- 这项研究将为新型风险适应PCa预防诊所的心理社会影响提供关键的见解.
- 调查结果将为制定全面的预防策略和支持PCa风险增加的男性提供信息.
- 这项研究旨在改善高风险人群的心理健康和遵守预防建议.
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