自闭症儿童和青少年视觉空间工作记忆的发展变化
Yu-Ju Lin1,2,3, Yu-Yu Wu4, Wen-Che Tsai1,2
1Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan.
Psychological medicine
|July 20, 2025
概括
与典型的发展对照组 (TDC) 相比,患有自闭症谱系障碍 (ASD) 的儿童和青少年表现出持续的视觉空间工作记忆 (WM) 缺陷. 虽然这两组随着时间的推移都在改善,但自闭症患者在空间WM中经历了较弱的与年龄相关的增长.
科学领域:
- 神经发育障碍 神经发育障碍
- 认知心理学 认知心理学
- 发育神经科学的发展神经科学.
背景情况:
- 有限的纵向数据存在于自闭症谱系障碍 (ASD) 中视觉空间工作记忆 (WM) 的发展.
- 了解这些发展轨迹对于有针对性的干预至关重要.
研究的目的:
- 研究患有自闭症儿童和青少年视觉空间WM的纵向变化.
- 为了比较自闭症和典型发育个体之间的发展轨迹.
主要方法:
- 使用剑桥神经心理测试自动化电池评估了123名自闭症和145名典型发育的儿童/青少年.
- 利用线性混合模型和脊柱回归来分析2-9年的变化,考虑年龄,自闭症诊断和相互作用.
主要成果:
- 自闭症患者在空间和一些视觉任务上的表现总是比对照组的表现更差.
- 两组患者随着时间的推移都出现了改善,与年龄相关的显著相互作用.
- 在模式识别记忆 (PRM) 和空间跨度 (SSP) 中发现了显著的年龄-ASD相互作用.
结论:
- 自闭症儿童和青少年表现出持续的视觉空间工作记忆缺陷.
- 与典型发育的同龄人相比,他们在视觉空间WM中显示出较弱的与年龄相关的改善.
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