儿童肥胖对不同骨折部位的影响
Wentao Yang1, Zhiyu Zhou2, Wei Gu3
1Department of Endocrinology, Children's Hospital of Nanjing Medical University, Nanjing, 210008, China.
Scientific reports
|July 20, 2025
概括
儿童肥胖与更高的骨折风险有关,特别是在下肢. 肥胖儿童的骨折几率明显增加,突出了针对性预防策略的必要性.
科学领域:
- 儿科 儿科 儿科
- 整形外科 整形外科 整形外科
- 公共卫生 公共卫生
背景情况:
- 在全球范围内,儿童肥胖的患病率正在上升,这给健康带来了重大挑战.
- 肥胖儿童可能面临骨折的风险增加,但研究结果不一致.
- 有限的研究已经探索了儿童体质指数 (BMI) Z-分数,肥胖和特定骨折部位之间的关系.
研究的目的:
- 研究住院儿童的BMI Z-score,肥胖和骨折风险之间的关联.
- 分析各种骨折位置 (下肢,上肢,轴,头部) 的BMI Z-score和肥胖率的差异.
- 为了比较患有骨折的儿童和健康的对照组之间的骨折风险因素.
主要方法:
- 对17942名骨折儿童和3219名健康儿童的回顾性分析.
- 数据收集包括年龄,性别,骨折部位,BMI Z-score和脂质资料.
- 使用的统计分析包括单向ANOVA,t-test,Chi-square测试,倾向得分匹配和后勤回归.
主要成果:
- 患有下肢骨折的儿童的BMI Z-score (0.58 ± 1.74) 和肥胖率 (20.20%) 是最高的.
- 头部骨折与最低的BMI Z-score (-0.02 ± 1.52) 和肥胖率 (8.42%) 有关.
- 与健康对照人群相比,骨折儿童的BMI Z-score (2.43 ± 1.22对比0.15 ± 1.43),肥胖率 (62.97%对比8.61%) 和脂质失调率 (31.22%对比24.67%) 显著提高.
- 后勤回归显示BMI Z-score是骨折风险的重要预测因素 (OR = 4.89,P < 0.001).
结论:
- 儿童下肢骨折与较高的BMI Z-分数和肥胖症密切相关.
- 较高的BMI Z-分数,肥胖和脂质失调是儿童骨折的重要危险因素.
- 这些发现强调了体重管理在儿童骨折预防中的重要性,特别是在下肢受伤方面.
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