尼福帕姆的滥用:法国的一项横截面研究
E Barat1,2, E Lacroix3, A Gillibert3
1Department of Pharmacy, CHU de Rouen, Rouen, France.
European journal of pain (London, England)
|July 21, 2025
概括
尼福帕姆的使用显著增加,特别是在15岁以下,65岁以上,患者或处于不利社会经济地位的患者中. 这项研究突出了nepopam的广泛不适当的处方,特别是在禁用组.
科学领域:
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
- 卫生经济学 卫生经济学
背景情况:
- 尼福帕姆是一种非阿片类止痛药.
- 在禁忌的人群中,尼福帕姆的处方日益增加,引发了对适当使用的担忧.
- 这项研究评估了法国的nefopam使用模式,重点关注年龄,和社会经济地位.
研究的目的:
- 分析法国内福帕姆使用的趋势和模式.
- 为了确定nefopam是否被处方给禁忌或脆弱的患者群体.
- 评估nefopam相对于其他止痛药的市场份额变化.
主要方法:
- 从2016年1月到2022年12月进行的回顾性观察研究.
- 使用来自法国国家医疗保险信息系统的数据.
- 根据患者人口统计 (年龄,状况) 和社会经济因素分析了nefopam发行数据.
主要成果:
- 在2016年至2022年期间,nefopam的使用量激增了121.7%,使其市场份额增加到11.6%.
- 在15岁以下 (2.8倍) 和65岁以上 (1.7倍) 的患者中观察到尼福帕姆使用的显著增加.
- 在患者 (1.7倍) 和社会经济地位不利的患者 (1.2倍) 中,使用量也增加了.
结论:
- 显而易见的是,尼福帕姆的广泛不适当使用,特别是在禁忌和弱势群体中.
- 口服内福帕姆的日益增加的可用性可能会加剧这些关于处方模式的问题.
- 密切的国家和欧洲监测对于管理nepopam使用和为未来的法规提供信息至关重要.
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