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绝对和相对握力与中国中老年人群认知表现的关联

Yuanjun Zeng¹, Zhenxue Song¹, Ling Zhang¹

¹Department of Epidemiology and Health Statistics, School of Public Health, Qingdao University, Qingdao, China.

Journal of Alzheimer's disease : JAD

|July 21, 2025

概括

保持更高的握力与老年人的认知衰退速度较慢有关. 较低的握力轨迹与更快的认知恶化相关,表明握力作为认知健康标志物.

科学领域:

老年学是一门学科.
神经科学是一个神经科学.
生理学生理学生理学

背景情况:

最近的元分析表明,握力 (GS) 和认知之间存在复杂的联系.
研究证实了身体组成和GS之间的显著相关性.

研究的目的:

研究握力轨迹与认知功能之间的纵向关系.
与认知变化相关的绝对和相对握力之间的区别.

主要方法:

利用了2549名参与者参与的中国健康与退休长度研究 (CHARLS) 的数据.
采用基于组的轨迹建模 (GBTM) 来识别抓地力轨迹.
使用定向环形图 (DAG) 和概括估计方程 (GEE) 模型来分析关联,调整混因素.

主要成果:

确定了三个不同的相对握力轨迹:低衰减 (32.29%),中等衰减 (50.69%) 和高衰减 (17.03%).
在绝对握力方面观察到类似的下降趋势.
在所有握力轨迹组中发现了统一的五年认知下降,握力变化和认知功能之间有显著的相互作用效应 (p < 0.001).

结论:

较低的握力轨迹与中年和老年人的加速认知衰退有关.
较高的握力轨迹与较慢的认知恶化有关.
握力可以作为监测老年人群认知健康的实际指标.

关键词:

阿尔茨海默病的疾病阿尔茨海默病的疾病.衰老的衰老衰老的衰老认知功能认知功能抓地力抓地力抓地力抓地力

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