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Updated: Sep 14, 2025

Using Human Induced Pluripotent Stem Cell-derived Hepatocyte-like Cells for Drug Discovery
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肝细胞染色体P450的转化和体内表型化:对预测精准医学和个性化疗法的影响

Shakir Ali1, Cem Aygun2, Ibrahim Halil Bahcecioglu3

  • 1Department of Biochemistry, School of Chemical and Life Sciences, Jamia Hamdard, Hamdard Nagar, New Delhi, India.

Hepatology forum
|July 21, 2025
PubMed
概括

细胞P450 (CYP) 酶活性,对于药物代谢至关重要,有显著的变化. 在体内CYP表型,测量代谢物/药物比率,对于优化药物剂量和确保患者安全至关重要,特别是在慢性肝病中.

关键词:
在CYP表型化方面.药物代谢 药物代谢个性化治疗是个性化的治疗.精准医学是一门精准医学.

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