B 枝状视网膜静脉封闭的长期结果:5年随访
İlkay Kiliç Müftüoğlu1, Natasha Mayer2, Katherine DU2
1Department of Ophthalmology, İstanbul Training and Research Hospital, İstanbul, Turkiye.
Turkish journal of medical sciences
|July 21, 2025
概括
五年来,静脉内抗VEGF注射有效改善了视力,并减少了分支视网膜静脉封闭 (BRVO) 患者的黄斑胀. 一个初始的加载剂量疗法增强了这些积极的结果.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 血管疾病 血管疾病
背景情况:
- 分支视网膜静脉封闭 (BRVO) 是一种常见的视网膜血管疾病.
- 长期结果和BRVO的最佳治疗策略需要进一步研究.
研究的目的:
- 为了评估新诊断的BRVO患者的5年后的结果,他们接受了静脉内抗VEGF注射.
- 为了比较不同抗VEGF治疗方案的疗效.
主要方法:
- 对97只眼睛的回顾性图表审查,新诊断的BRVO.
- 评估最佳校正的视力敏度 (BCVA),中央黄斑厚度 (CMT) 和治疗细节.
- 基于初始加载剂量治疗结果的结果比较.
主要成果:
- 在所有随访中,平均BCVA改善,平均CMT显著下降 (p < 0.05).
- 33%的眼睛在5年后获得了3条BCVA线;平均总注射量为19.
- 与非加载剂量方案相比,初始加载剂量导致显著更大的BCVA增益和CMT减少.
结论:
- 内抗VEGF疗法在改善BRVO患者的视觉和解剖结果方面显示出长期的有效性.
- 一个初始的治疗方案,即三次充满剂量的抗VEGF,与卓越的视觉和解剖结果有关.
相关概念视频
Open Angle Glaucoma: Treatment
577
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
577
Angle Closure Glaucoma: Treatment
691
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
691
Glaucoma: Overview
771
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
771


