评估帕金森病患者的听觉感知功能
Sherifa Ahmed Hamed1, Mohamed Ahmed Abd-ElHamed1, Amira Mohamed Oseily2
1Department of Neurology and Psychiatry, Assiut University Hospital Assiut, Egypt.
American journal of neurodegenerative disease
|July 21, 2025
概括
中央听觉处理 (CAP) 障碍在早期帕金森病 (PD) 中很常见,影响诸如语音感知和时间序列等技能. 这些缺陷与认知能力下降相关,可能源于多巴胺缺乏.
科学领域:
- 神经科学是一个神经科学.
- 听力学 听力学是指听力学.
- 神经学 神经学
背景情况:
- 听力障碍是帕金森病 (PD) 的公认表现.
- 在PD患者中,中央听觉处理 (CAP) 功能需要彻底评估.
- 确定CAP功能障碍的预测因素对于了解PD进展至关重要.
研究的目的:
- 评估帕金森病 (PD) 患者中中央听觉处理 (CAP) 功能.
- 为了确定在PD中CAP功能障碍的预测因素.
- 评估用于评估PD中CAP的特定测试的有用性.
主要方法:
- 一项涉及35名PD患者和25名对照者的横截面研究.
- 使用标准化尺度 (Hoehn和Yahr,BDI-II,MMSE,MoCA) 评估PD严重程度,抑郁症和认知功能.
- 使用听力测量,语音数字 (DDT),持续时间模式 (DPT) 和语音在噪音中 (SPIN) 测试来评估CAP.
主要成果:
- 与对照人群相比,PD患者在高频率下表现出较差的认知和听力损伤.
- 在PD患者的DDT,DPT和SPIN测试中观察到显著的缺陷.
- 这些CAP障碍与认知缺陷独立相关.
结论:
- 中央听觉处理 (CAP) 功能障碍在帕金森病 (PD) 的早期阶段很普遍.
- 障碍包括听觉歧视,空间感知,双耳集成,时间排序和选择性注意力.
- 多巴胺缺乏和神经退行性病理是PD中CAP损伤的潜在原因.
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