初级恶性气管瘤的诊断和多模式治疗
Benoit Jacques Bibas1,2,3, Mariana Rodrigues Cremonese1,2, Paula Duarte D'Ambrosio1,2
1Thoracic Surgery Department, Hospital Municipal Vila Santa Catarina Dr. Gilson de Cássia Marques de Carvalho, São Paulo, Brazil.
初级恶性气管瘤 (PMTTs) 是罕见的,但需要多学科的方法. 管理平衡手术切除,内镜干预和辅助疗法,以获得最佳的患者结果.
科学领域:
- 胸部外科手术 胸部外科手术
- 在瘤学瘤学.
- 肺部病理学 肺部病理学
背景情况:
- 主要恶性气管瘤 (PMTTs) 是罕见的,占癌症的<0.5%.
- 常见的类型包括腺囊性癌和状细胞癌.
- 由于气管储备延迟诊断,症状发病时间较晚.
研究的目的:
- 审查PMTT管理的当前知识.
- 为了确定未来研究的证据缺口.
- 为这些罕见瘤的临床实践提供信息.
主要方法:
- 关于PMTT管理的综合文献综述.
- 对手术切除,内镜干预和辅助疗法的分析.
- 诊断成像和支气管镜评估的评估.
主要成果:
- 在可行的情况下,优先进行重建的手术切除.
- 切除的长度会影响解剖风险;R0与R1的决定涉及患者的解剖学和放射治疗.
- 内镜干预对于不可切除或不可手术的病例是缓和的.
结论:
- 综合手术,内镜和辅助治疗的多学科管理至关重要.
- 预后取决于组织学,切除边缘和患者因素.
- 有限的证据需要依赖于回顾性数据和经验.
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