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Updated: Sep 14, 2025

Optogenetic Phase Transition of TDP-43 in Spinal Motor Neurons of Zebrafish Larvae
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使用循环RNA向氨基缩性侧面硬化症中有毒的RNA结合蛋白

Anne Kruse Hollensen1, Matilde Helbo Sørensen1, Sofie Vesterbæk Thomsen1

  • 1Department of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus C, Denmark.

Molecular therapy. Methods & clinical development
|July 21, 2025
PubMed
概括

循环RNAs (circRNAs) 为肌缩侧面硬化症 (ALS) 提供了一个新的治疗策略. 这项研究表明,工程化circRNAs可以降解涉及ALS的与疾病相关的RNA结合蛋白 (RBPs).

关键词:
这就是ALS.E3 泛基因合酶RC3H2H2 的使用.这就是FUS FUS.环形RNA PROTAC 的时间.导致疾病的RBPs.hnRNPA1 在线观看

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