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内脏脂肪指数与膀过活的关联:来自NHANES 2007-2018年的见解
Panpan Jiao1,2, Xinmiao Ni1,2, Jingsong Wang1,2
1Department of Urology, Renmin Hospital of Wuhan University, Wuhan, China.
Translational andrology and urology
|July 21, 2025
概括
较高的内脏脂肪指数 (VAI) 与过度活跃膀 (OAB) 的风险增加有关. 这项研究发现VAI和OAB发生之间存在非线性积极的剂量反应关系.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 代谢健康 代谢健康
- 流行病学 流行病学
背景情况:
- 过度活性膀 (OAB) 病原体可能涉及肥胖.
- 内脏脂肪和OAB之间的联系需要进一步调查.
研究的目的:
- 在大量人群中分析内脏脂肪指数 (VAI) 和OAB之间的关系.
- 为了确定内脏脂肪积累和OAB症状之间的关联.
主要方法:
- 利用了NHANES数据库 (2007-2018) 中13694名参与者的数据.
- 使用WC,BMI,TG和HDL-c计算的VAI.
- 使用OABSS (≥3) 定义的OAB,并分析了与加权多变量逻辑回归和受限制立方线 (RCS) 分析的关联.
主要成果:
- 在VAI和OAB之间观察到显著的非线性积极剂量反应关系 (P<0.001).
- 在VAI的最高四分位数显示出与OAB发生的显著关联 (P<0.05).
- 在VAI = 1.41.1时确定了OAB风险的拐点.
结论:
- 由VAI量化的内脏脂肪率与OAB的可能性增加有显著的关联.
- 调查结果表明,VAI可以成为OAB管理策略中的一个有价值的标记.
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