超声导向修改的胸腹神经阻塞用于腹腔镜囊解压中的术后止痛:一项随机双盲对照试验
Mengning Wan1, Jun Dong1, Ke Wei1
1The Department of Anesthesiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Frontiers in medicine
|July 21, 2025
概括
超声导向修改型胸腹神经阻塞 (M-TAPA) 在经过腹腔镜囊解压的患者中显著降低了术后疼痛和阿片类药物的使用. 这项研究证明了M-TAPAPA.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 疼痛管理 疼痛管理
- 区域麻醉地区麻醉
背景情况:
- 手术后的疼痛是腹腔镜囊解压 (LRCD) 后的一个重大挑战.
- 现有的LRCD疼痛管理策略缺乏普遍接受.
- 区域神经阻塞提供有针对性的缓解疼痛,但它们在LRCD中的有效性需要进一步评估.
研究的目的:
- 评估单边超声导向修改型胸腹神经阻塞 (M-TAPA) 在LRCD后减轻术后疼痛的疗效.
- 评估M-TAPA对阿片类药物消费和相关副作用的影响.
- 确定M-TAPA在改善LRCD后患者康复方面的潜在益处.
主要方法:
- 一个随机,双盲,受控试验,涉及61名接受LRCD的患者.
- 患者被分配到接受安慰剂的M-TAPA组 (n=31) 或控制组 (n=30).
- 术后疼痛使用数值评分表 (NRS) 测量了48小时的疼痛,以及阿片类药物消费和副作用.
主要成果:
- 与对照组相比,M-TAPA组在所有评估时间点上表现出明显较低的NRS疼痛得分.
- 在48小时内,M-TAPA组观察到阿片类药物消费的大幅减少 (22%).
- 在M-TAPA组需要更少的抗药物,并没有报告M-TAPA相关的并发症.
结论:
- 单边M-TAPA是一种有效的干预措施,用于管理LRCD后的术后疼痛.
- 在LRCD患者中,M-TAPA显著降低了阿片类药物需求和相关副作用.
- 这种神经阻塞技术在LRCD手术中有望改善恢复结果.
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