使用低剂量尼沃卢马布的新辅助化疗导致非小细胞肺癌的完整病理反应

Prasanth Penumadu1, Prasanth Ganesan2, Dhanapathi Halanaik3

  • 1Department of Surgical Oncology, Sri Venkateswara Institute of Cancer Care and Advanced Research, Tirupati, India.

概括

在局部晚期非小细胞肺癌中,新辅助剂低剂量尼沃卢马布与化疗实现了完全的病理反应. 这种方法在资源有限的环境中为肺癌治疗提供了潜在的经济性免疫疗法选择.

相关概念视频

Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists01:28

Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists

Neurokinin 1 (NK1) receptors are distributed across the GI tract, vagal afferents, and key CNS regions including the central vomiting center and chemoreceptor trigger zone (CTZ) Chemotherapy agents stimulate enterochromaffin cells in the gastrointestinal (GI) tract to release large amounts of substance P (SP). SP is a neuropeptide released by specific sensory nerves in response to many different stressors, including those in the GI mucosa affected by chemotherapy.  SP binds and activates...
264
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
8.0K