一个随机对照的有效性试验的研究协议,THRIVE的小组和同行辅导,以促进自杀恢复危机稳定中心的危机稳定中心
Jennifer D Lockman1,2, Anthony R Pisani3,4, M Alexis Kirk5
1Department of Psychiatry and Behavioral Neurobiology, Depression and Suicide Center, University of Alabama at Birmingham, United States.
Contemporary clinical trials communications
|July 21, 2025
概括
这项研究试验了THRIVE,这是危机稳定中心 (CSC) 的新干预措施,以改善自杀预防. 在社区精神卫生环境中,THRIVE显示出增强治疗参与度的前景.
科学领域:
- 心理健康研究 心理健康研究
- 心理干预 心理干预
- 基于社区的护理
背景情况:
- 危机稳定中心 (CSCs) 为预防自杀提供了紧急部门的替代方案.
- 需要新的,以恢复为重点的干预措施,使CSC能够加强自杀预防.
- 988自杀预防救生线可以通过CSC扩展.
研究的目的:
- 检查 CSCs 恢复,希望,人际联系,价值观和参与 (THRIVE) 干预措施的可行性,可接受性和目标参与.
- 适应,试点和测试THRIVE,为全面的有效性试验做准备.
- 调查THRIVE对治疗启动和与目标因素 (如挫败的归属感和感知到的负担) 的接触的影响.
主要方法:
- 一个分阶段的方法:I阶段 (实施设计和影响模型-MADI) 适应 (n=25).
- 第二阶段:通过利益相关者的反和试点试验 (n=20) 来评估可行性和可接受性.
- 第三阶段:试点随机有效性试验 (n=162) 将THRIVE+常规护理与单独的常规护理进行比较,在基线,出院,1个月和3个月进行评估.
主要成果:
- 目前正在进行试点数据收集和分析.
- 研究方案旨在为更大规模的疗效试验提供信息.
- 这项研究涉及基于社区的实践合作伙伴,是NIMH在CSC中赞助的第一个RCT.
结论:
- 目前正在严格测试THRIVE干预措施的潜力,以提高CSC的自杀预防服务.
- 结果将指导在社区心理健康中实施有效的,以康复为重点的心理干预.
- 这项研究有助于了解如何将研究纳入实践,以改善心理健康结果.
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