在鼻腔导管氧气治疗的患者中,治疗COVID-19的康复性血疗法
Ran Chen1,2, Yingying Zhang2,3, Ying Liu2,3
1Cixi Biomedical Research Institute, Wenzhou Medical University, Zhejiang, China.
Journal of thoracic disease
|July 21, 2025
概括
康复性血疗法显著降低了接受氧气治疗的COVID-19患者的死亡率. 这种治疗改善了缺氧患者的生存率,证明了其在重症监护机构的有效性.
科学领域:
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
- 免疫治疗是一种免疫疗法.
背景情况:
- 康复性血疗法 (CPT) 在降低COVID-19患者的死亡率方面显示出有前途.
- 氧气治疗,特别是鼻腔导管氧气,是低氧COVID-19患者的标准.
- 对于已经接受氧气治疗的患者中CPT疗效的数据有限.
研究的目的:
- 评估CPT在接受早期氧气治疗的COVID-19患者的疗效和安全性.
- 评估CPT对该患者群的死亡率和实验室参数的影响.
主要方法:
- 对接受CPT和标准护理的112名COVID-19患者的回顾性研究.
- 收集的人口统计,实验室测试和血剂量的数据.
- 主要结局:28天死亡率;次要结局:实验室参数.
主要成果:
- 28天死亡率在CPT治疗中为20%,在标准治疗中为44% (P=0.008).
- 在严重的COVID-19中,CPT的死亡率为34%,标准护理为59% (P=0.04).
- 在接受鼻腔导管氧气≥48小时的患者中,CPT的死亡率为21%,标准护理为42% (P=0.02).
结论:
- 在接受鼻腔导管氧治疗的COVID-19患者中,CPT显著降低了28天的死亡率.
- CPT是低氧COVID-19患者的安全有效的辅助疗法.
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