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Updated: Jun 14, 2026

A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells
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A Syngeneic Mouse B-Cell Lymphoma Model for Pre-Clinical Evaluation of CD19 CAR T Cells

Published on: October 16, 2018

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基于循环结构的新型CD19/CD22双标CAR-T疗法用于高风险的扩散性大B细胞淋巴瘤,呈现出血细胞淋巴细胞瘤:一个病例报告

Yuan Ye1, Shuhong Li2, Zhi Guo1

  • 1Department of Hematology, Affiliated Nanshan Hospital of Shenzhen University, Shenzhen, Guangdong, 518052, People's Republic of China.

Cancer management and research
|July 21, 2025
PubMed
概括

新的CD19/CD22 BS LoopCAR-T疗法对高风险的扩散性大B细胞淋巴瘤 (DLBCL) 与血细胞淋巴细胞瘤 (HLH) 有前途. 在一项患者病例研究中,这种治疗导致了完全缓解和持续的无病生存.

关键词:
CD19/CD22的目标是双重目标.仿制性抗原受体T细胞的T细胞.扩散大的B细胞淋巴瘤.血细胞性淋巴细胞化.

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