通过模拟卵巢癌癌前癌情景,定义由细胞外膀驱动的输卵管上皮质重编程

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Jared Sipes1,2, Didi Zha3, Sagar Rayamajhi1

  • 1Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas.

Cancer research communications
|July 21, 2025
PubMed
概括

卵巢癌小细胞外囊泡 (sEVs) 改变人类输卵管上皮质 (hFTE) 基因表达,促进免疫信号变化. 这种微流体模型揭示了卵巢管中早期病原发生的事件,卵巢癌的起源.

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