在术后期口香糖的影响:系统性审查和元分析
Calandra Li1, Akhil Nair1, Xi Ming Zhu2
1Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
ANZ journal of surgery
|July 21, 2025
概括
口香糖有效地缓解了手术后脏 (POI) 症状,减少了康复时间和住院时间. 这种低成本的干预措施为手术患者提供了显著的好处,经过元分析证实了这一点.
科学领域:
- 胃肠病学 胃肠病学
- 术后恢复 术后恢复
- 基于证据的医学基于证据的医学.
背景情况:
- 手术后阴道 (POI) 是手术后的一种常见并发症,其特点是胃肠道运动能力受损.
- POI导致感染,死亡率和医疗保健成本的风险增加.
- 减轻POI的有效干预对于患者的治疗结果至关重要.
研究的目的:
- 为了评估口香糖在缓解POI症状方面的有效性.
- 进行元分析以估计口香糖在POI结果上的整体影响大小.
主要方法:
- 在主要数据库 (MEDLINE,EMBASE,CINAHL,Web of Science,Scopus) 中进行了系统的文献搜索.
- 包括英语随机对照试验 (RCT) 涉及成年手术患者.
- 使用GRADE系统评估研究质量,并在外科手术子组内进行元分析.
主要成果:
- 在1925年的初始引用中,有43项研究符合纳入标准.
- 分析显示,在一般,结肠直肠和OBGYN/妇科手术队伍中,第一次浮和排便的时间显著减少.
- 具体来说,减少到浮的时间从-6.52到-7.4小时,减少到排便的时间从-9.71到-18.64小时.
结论:
- 牙是一种安全,低成本的干预措施,可以显著减少POI症状,缩短住院时间.
- 分析证实了口香糖对于POI管理的临床相关性.
- 需要使用标准化协议进行进一步的研究,以完善效果大小估计并减少异质性.
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