围部植入炎管理的测量涂层策略:临床影响和分类方法
Marta M A Pereira1, Rafael Scaf de Molon2, Valentim A R Barão3
1Department of Dental Materials and Prosthodontics, São Paulo State University/UNESP, Araraquara, São Paulo, Brazil.
Journal of periodontology
|July 21, 2025
概括
开发用于牙科植入物的抗微生物涂层需要明确的功能目标. 本综述对预防周植入炎 (疾病发病) 和治疗已确定的感染的策略进行了分类,以指导未来的材料开发.
科学领域:
- 生物材料科学 生物材料科学
- 牙科植入物学 牙科植入物学
- 微生物学 微生物学
背景情况:
- 牙周植入体炎是一种由牙科植入物上的异生物生物膜引起的炎症状况.
- 植入物表面上的细菌粘附会导致骨质逐渐丧失.
- 开发有效的抗微生物涂层对于对抗周植入炎至关重要.
研究的目的:
- 建议对周植入炎的抗菌涂层策略进行明确的分类.
- 对抗微生物涂料的预防和治疗方法进行区分.
- 根据其预期的功能指导涂料的开发.
主要方法:
- 对围植入体炎的预防和治疗概念的审查.
- 分析牙植入物组件的物理化学特性和生物要求.
- 基于功能 (预防与治疗) 的涂层策略的分类.
主要成果:
- 预防性涂层旨在通过无限期耐受口腔环境来阻止疾病的发病.
- 处理涂层必须直接作用于受感染的部位,可能需要刺激反应药物释放.
- 涂层特性不能影响骨生物材料或软组织生物材料的相互作用.
结论:
- 抗微生物涂料的商业成功是有限的.
- 清晰地对涂层功能进行分类对于成功开发至关重要.
- 未来的抗微生物涂层需要考虑临床潜力的生物和化学挑战.
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