经过成功的EUS引导胃肠静脉切除术后的胃肠囊:从国际队列中学习的初步教训
Antonio Mendoza Ladd1, Michel Ladna2, Luke Pecha1
1Department of Internal Medicine, Division of Gastroenterology, University of California.
胃肠结肠 (GECF) 是一种罕见的,在EUS导向胃肠静脉切除术 (EUS-GE) 后出现的晚期不良事件. 这项研究描述了16例病例,突出了内镜管理的成功以及对GECF原因的进一步研究的需要.
科学领域:
- 胃肠病学 胃肠病学
- 干预性内镜检查是干预性的内镜检查.
- 手术瘤学并发症 手术瘤学并发症
背景情况:
- 以EUS为指导的胃肠静脉切除术 (EUS-GE) 是一种已知的胃出道阻塞 (GOO) 的治疗方法.
- 由于患者的预后,EUS-GE的长期不良事件 (AE) 没有得到充分记录.
- 胃肠结肠 (GECF) 被确定为EUS-GE.的潜在晚期AE.
研究的目的:
- 描述一组在EUS-GE后发展出GECF的患者.
- 分析GECF的特点,管理和成果.
- 确定GECF发展的潜在风险因素和机制.
主要方法:
- 从10个大批量中心对16名GECF患者进行了回顾性分析.
- 收集的数据包括人口统计数据,EUS-GE适应症,状腺细节和管理策略.
- 分析了结果和后续数据.
主要成果:
- 从EUS-GE诊断到GECF诊断的平均间隔为4-8周.
- 胰腺腺癌是最常见的GOO原因;横向结肠是频繁的管部位.
- 在16名患者中,内镜治疗在13名患者中取得了成功;这组患者的死亡率很高.
结论:
- 这是第一个将GECF描述为EUS-GE的晚期AE的队列研究.
- 确切的机制尚不清楚,但怀疑是无意的结肠穿刺或中结肠陷入.
- 需要进一步的研究才能充分描述这种罕见的不良事件.
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