真正的昆虫捕食者中的微生物的多样性,传播和动物感染潜力
Hongfeng Li1, Zheng Y X Huang2, Jie Lan1
1Department of Microbiology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Nature communications
|July 21, 2025
概括
真正的昆虫食者 (Eulipotyphla) 承载着众多病毒,和刺与人类病毒有密切的关系. 这些哺乳动物是跨物种病毒传播的关键,构成公共卫生风险.
科学领域:
- 微生物学 微生物学
- 病毒学 病毒学
- 生态生态学 生态生态学
背景情况:
- 包含500多个物种的Eulipotyphla (真实食虫) 序列在微生物多样性及其在传染病传播中的作用方面未得到充分研究.
- 了解昆虫食者中的微生物群落对于识别动物传染病的潜在来源至关重要.
研究的目的:
- 综合分析食虫的微生物多样性,并评估它们在野生宿主之间病毒传播中的作用.
- 调查昆虫食者与人类之间病毒传播的可能性.
主要方法:
- 从1903年至2023年编制了一个大型数据集,包含40多万条关于食虫者和相关微生物的记录.
- 进行了元分析,以识别Eulipotyphla序列内的独特的微生物和病毒.
- 分析了病毒共享网络和影响跨物种传播的生态因素.
主要成果:
- 昆虫类有941种独特的微生物,其中病毒占60%,主要存在于和刺中.
- 在昆虫捕食者中发现的病毒,特别是和刺,在基因上与人类病毒有关,这表明双向传播.
- 昆虫类仅次于蝙蝠在哺乳动物群体中病毒共享的中心位置,具有很高比例的跨境传播病毒.
结论:
- 昆虫类动物具有显著的微生物多样性,并在病毒传播中发挥关键作用,作为动物性病原体的潜在储库.
- 诸如饮食和息地多样性等生态因素显著影响昆虫的内部和昆虫的跨物种病毒传播.
- 这项研究强调了昆虫食者在影响哺乳动物,包括人类的病毒的出现和传播方面对公共卫生的重要性.
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