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Updated: Sep 14, 2025

Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry
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Published on: November 29, 2013

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在Hsp90功能中,ATP起着结构性作用

Michael Reidy1, Daniel C Masison2

  • 1Laboratory of Biochemistry and Genetics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA. michael.reidy@nih.gov.

Nature communications
|July 21, 2025
PubMed
概括

氨酸三酸盐 (ATP) 的结合,而不是水解,对于Hsp90的护送功能至关重要. ATP充当结构链接器,通过与氨酸R380.的相互作用稳定Hsp90.

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