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Updated: Sep 14, 2025

Incorporation of a Survivable Liver Biopsy Procedure in Mice to Assess Non-alcoholic Steatohepatitis NASH Resolution
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在代谢功能障碍相关的脂肪肝炎中,semaglutide对代谢,炎症和纤维细胞路径进行调节

Maximilian Jara1, Jenny Norlin2, Mette Skalshøi Kjær1

  • 1Novo Nordisk, Clinical Development, Søborg, Denmark.

Nature medicine
|July 21, 2025
PubMed
概括

在代谢功能障碍相关的脂肪肝炎 (MASH) 模型中,通过减少纤维化和炎症,塞马格卢提德治疗改善了肝脏健康. 它还使患者的关键蛋白质正常化,表明恢复到健康的代谢状态.

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