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Updated: Sep 14, 2025

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA
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Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA

Published on: August 21, 2016

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改进的多祖先精细映射识别出底层分子特征和疾病风险的cis-regulatory变异

Zeyun Lu1,2,3, Xinran Wang4,5, Matthew Carr4

  • 1Center for Genetic Epidemiology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. zeyunlu@usc.edu.

Nature genetics
|July 21, 2025
PubMed
概括

新的SuShiE模型提高了识别不同祖先分子特征的因果遗传变异的精度. 这种方法改善了分子定量特征位点 (molQTL) 研究和关联分析中的基因发现.

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