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Updated: Sep 14, 2025

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异常的Notch信号促进了食道状细胞癌中的瘤血管生成

Cainan Li1, Pujie Wu1, Xiaoting Xie1

  • 1Department of Etiology and Carcinogenesis, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

Signal transduction and targeted therapy
|July 21, 2025
PubMed
概括

异常的Notch信号驱动食道癌血管新生通过上调USP5,这稳定了STAT3.3. 与化疗一起抑制USP5显示出治疗这种侵袭性癌症的前景.

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