骨质强度和骨健康:一个范围审查
Ameya Kabra1, Wendy B Katzman2, Nancy E Lane3
1Faculty of Science, University of Waterloo, Waterloo, Canada.
概括
强度运动可能不会显著增加骨矿物质密度,对其安全性和有效性的证据有限. 需要更多高质量的研究来证实对骨强度的益处.
科学领域:
- 骨健康研究 骨健康研究
- 肌肉骨干预措施 肌肉骨干预措施
- 老年医学 老年医学
背景情况:
- 奥斯泰强公司声称,每周在专有机器上进行运动可以提高骨矿物质密度.
- 医疗保健提供者需要证据来解决患者对OsteoStrong有效性和安全性的询问.
- 在全球范围内OsteoStrong特许经营权的日益增长,需要对支持研究进行审查.
研究的目的:
- 综合目前关于OsteoStrong疗效和安全性的研究.
- 为医疗保健专业人员提供基于证据的信息,用于患者咨询.
- 评估支持OsteoStrong关于骨健康的说法的科学文献.
主要方法:
- 对五个数据库进行快速范围检查.
- 包括与OsteoStrong机器相关的测量跌倒,骨折或骨强度的研究.
- 数据选和抽象由两个独立审查员进行.
主要成果:
- 从1388个初步结果中,包括了9项研究;五项是未发表的摘要.
- 七项研究是观察性,两项是随机试验,比较OsteoStrong与运动;没有试验比较OsteoStrong与对照组.
- 骨矿物质密度 (BMD) 的影响不一致;关于骨折,跌倒和不良事件的数据有限.
结论:
- 关于OsteoStrong的研究主要是具有潜在偏差的小型观察性研究.
- 对骨强度的影响不一致,安全性数据有限.
- 需要高质量的研究来验证OsteoStrong的说法并评估患者的安全性.
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