在乳牛的干旱期和产前期开始时抗菌成分度的变化
Jirapat Jaisue1, Jinkun Sun1, Nur Laili Marufah1,2
1Graduate School of Integrated Sciences for Life, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan.
Animal science journal = Nihon chikusan Gakkaiho
|July 22, 2025
概括
干旱期间奶牛的抗菌成分动态受体细胞计数 (SCC) 的影响. 干燥时的下部SCC与有益的抗微生物变化有关,突出显示了干燥前的乳头健康的重要性.
科学领域:
- 兽医免疫学 兽医免疫学
- 乳制品科学 乳制品科学
- 哺乳腺生物学 哺乳腺生物学
背景情况:
- 干旱时期对于乳腺内置和乳牛的免疫功能至关重要.
- 了解这一阶段抗微生物成分 (AMC) 变化对于乳腺健康至关重要.
- 体细胞计数 (SCC) 是乳腺炎症的指标,可能会影响AMCs.
研究的目的:
- 在干旱期间调查奶牛中各种AMC的动态.
- 评估初始SCC水平对整个干旱期和产后AMC度的影响.
- 为了确定受SCC和分娩影响的关键AMC.
主要方法:
- 牛奶样本从荷尔斯泰因牛群中采集在四个时间点:干燥,分娩前,分娩后立即和分娩后一周.
- 在干旱时期开始时,奶牛被分为低SCC和高SCC组.
- 测量了SCC度,语言抗微生物,乳酸氧化酶,乳酸铁素,cathelicidin-7,S100A7和S100A8的度.
主要成果:
- 在低SCC的奶牛中,SCC和语言抗菌增加了分娩前期,而乳酸氧化酶和乳酸增加了分娩前期,但降低了分娩后期.
- 在这两组中,cathelicidin-7,S100A7和S100A8在分娩后增加.
- S100A7在低SCC组产前和产后立即较高,而S100A8在低SCC组产前和1周产后较低.
结论:
- 某些AMC在干燥后和分娩后立即增加,表明有活跃的免疫反应.
- 产前SCC水平显著影响产后AMC概况.
- 在干旱期之前减轻乳腺炎症对于优化乳腺健康和免疫功能至关重要.
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