疲劳及其与中国多发性硬化症患者焦虑和抑郁的相关性
Han Wang1,2, Rongrong Wang1,2, Runze Zhao3
1Department of Neurology, Yan'an University Medical College No. 3 Affiliated Hospital, Xianyang, China.
Frontiers in neurology
|July 22, 2025
概括
超过一半的多发性硬化症 (MS) 患者经历了致残的疲劳. 这种疲劳与中国患者的焦虑和抑郁等心理因素密切相关.
科学领域:
- 神经学 神经学
- 免疫学 免疫学 免疫学
- 精神病学是一个精神病学.
背景情况:
- 多发性硬化症 (MS) 是一种慢性,免疫媒介的中枢神经系统疾病.
- 疲劳是MS (PwMS) 患者的普遍和衰弱症状.
- 包括抑郁,压力和焦虑在内的心理因素与PwMS的疲劳有关.
研究的目的:
- 调查中国PwMS的疲劳患病率和影响因素.
- 在这个人群中检查疲劳,焦虑和抑郁之间的相关性.
主要方法:
- 跨截面在线研究设计.
- 收集的人口统计和临床数据.
- 使用了修改后的疲劳影响量表 (MFIS),贝克焦虑量表 (BAI) 和贝克抑郁量表-II (BDI-II).
主要成果:
- 在366名PwMS中,55.7%的人报告感到疲劳.
- 较高的疲劳分数与年龄增加,疾病持续时间,焦虑和抑郁相关.
- 年龄,教育,就业,婚姻状况和疾病类型等因素影响了疲劳.
结论:
- 在中国PwMS中,疲劳的患病率很大,为55.7%.
- 在PwMS中,疲劳受到人口统计学和临床因素的显著影响.
- 在PwMS中,疲劳,抑郁和焦虑之间存在强烈的正相关性.
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