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同时的肺部感染和围腹:一个病例报告和文献综述
Lixin Guo1, Li Ma1, Wenjing Ren1
1Department of Respiratory Medicine, The Second Hospital of Jilin University, Changchun, Jilin, China.
Frontiers in immunology
|July 22, 2025
概括
一名患有持续呼吸道症状的糖尿病患者被诊断出患有罕见的无氧细菌感染. 针对性下一代测序 (tNGS) 识别了口腔无气体,从而有效地治疗了抗生素和排水.
科学领域:
- 传染性疾病 传染性疾病
- 微生物学 微生物学
- 肺部病理学 肺部病理学
背景情况:
- 一名64岁的男性患有2型糖尿病和高血压,出现了长期呼吸道症状,对抗生素无反应.
- 最初的调查表明肺部感染,但经验治疗失败了.
研究的目的:
- 报告一种罕见的隐性无氧细菌感染病例,呈现为周围腹和瘤.
- 突出针对性下一代测序 (tNGS) 在识别具有挑战性的病原体方面的诊断实用性.
主要方法:
- 临床病例介绍,包括详细的病史和诊断工作.
- 使用胸部计算机断层扫描 (CT) 进行初始成像.
- 雇员针对性下一代测序 (tNGS) 用于在唾液样本中识别病原体.
主要成果:
- 尽管有负面的唾液培养,但tNGS确定了多种口腔无气体作为致病剂.
- 患者患上了右侧围腹和瘤.
- 用美트로尼达和手术排水治疗导致在33天内完全解决临床和实验室问题.
结论:
- 在患有耐火性发烧性疾病的糖尿病患者中,应考虑隐性无氧感染.
- 周腹和肺可以是这种感染的罕见并发症.
- 在复杂的感染中,tNGS是识别无氧细菌的宝贵工具.
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