化学免疫疗法在先进的,PD-1耐火性皮肤状细胞癌:从两个免疫受损患者病例的见解
Golbarg Rahimi1, Gino K In1,2
1Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Case reports in oncological medicine
|July 22, 2025
概括
对于免疫功能低下患者的晚期皮肤状细胞癌 (cSCC),将化疗与PD-1抑制相结合可能克服对PD-1单一治疗的耐药性,在两个案例研究中显示出有希望的瘤控制.
科学领域:
- 在瘤学瘤学.
- 免疫治疗是一种免疫疗法.
- 皮肤病学 皮肤病学
背景情况:
- 皮肤状细胞癌 (cSCC) 是一种常见的癌症,在免疫功能低下的个体中具有高转移和死亡风险.
- 编程细胞死亡蛋白1 (PD-1) 抑制剂是标准治疗方法,但也可能出现初级耐药性.
- 目前正在探索组合疗法,以改善高级cSCC的结果.
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