在初级Sjögren综合征中脏参与:来自北印度的多中心研究
Scienthia Sanjeevani1, Pallavi Prasad2, Sourabh Sharma2
1Nephrology, Kalinga Institute of Medical Sciences, Bhubaneswar, IND.
在原发性Sjögren综合征中,脏参与往往被忽视,慢性管间炎是最常见的诊断. 早期脏评估对于及时治疗和预防疾病进展至关重要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 类风湿病学 类风湿病学
- 免疫学 免疫学 免疫学
背景情况:
- 在原发性Sjögren综合征 (pSS) 中,脏参与经常被低诊断.
- 关于pSS患者的表现和结果的数据有限.
- 早期发现功能障碍对于改善患者预后至关重要.
研究的目的:
- 突出了pSS患者综合性评估的重要性.
- 分析pSS患者的临床概况和结局.
- 强调活检在诊断和管理PSS并发症中的作用.
主要方法:
- 这是一项多中心的回顾性研究,分析了从2013年到2021年患有脏干扰的pSS患者.
- 审查了包括标准,生化测试和脏活检结果.
- 为了评估结果,收集了一年的后续数据.
主要成果:
- 研究了38名患者 (94.7%为女性,平均年龄为41.4岁).
- 降低的EGFR (<60毫升/分钟/1.73米2) 影响了63%的患者.
- 慢性管介质炎是最常见的活检发现 (36.3%).
结论:
- 慢性管介质炎是PSS中主要的脏表现.
- 许多病例在晚期被诊断出来,这强调了早期查的必要性.
- 及时诊断和治疗可以预防慢性病的进展.
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