Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Electrophysiology of Normal Cardiac Rhythm01:19

Electrophysiology of Normal Cardiac Rhythm

6.8K
The normal cardiac rhythm is a synchronized electrical activity that facilitates the regular and coordinated contraction of the heart muscle. This process is essential for efficient blood circulation throughout the body. The fundamental elements involved in establishing and maintaining this rhythm include the unique electrical properties of cardiac muscle cells, the sinoatrial (SA) node's pacemaker function, the specialized conducting system, and the ionic mechanisms underlying each phase...
6.8K
Specialized Characteristics of Cardiac Muscles01:27

Specialized Characteristics of Cardiac Muscles

2.8K
The primary role of cardiac muscles is to propel blood throughout the cardiovascular system. The cardiac muscle cells, or cardiomyocytes, exhibit specialized characteristics that allow them to perform this function.
Cardiac muscle cells are smaller than skeletal muscles, averaging 10–20 mm in diameter and 50–100 mm in length. However, they have large energy demands for continuous contraction and relaxation. This energy is almost exclusively derived from aerobic metabolism of energy...
2.8K
Conduction System of the Heart01:19

Conduction System of the Heart

9.9K
Autorhythmicity is a term that refers to the heart's inherent ability to generate electrical signals and instigate muscle contractions. This self-regulating conduction system within the heart consists of two key components: the pacemaker cells and specialized conducting cells.
The pacemaker cells are located in two primary nodes: the sinoatrial (SA) node and the atrioventricular (AV) node. The SA node pacemaker cells can autonomously depolarize, triggering an action potential that leads to the...
9.9K
Cardiac Action Potential01:30

Cardiac Action Potential

2.6K
Cardiac action potentials are essential for proper heart function, enabling the rhythmic contractions needed for adequate blood circulation. Nodal cells and Purkinje fibers, specialized for electrical conduction, generate these action potentials.
The cardiac action potential process involves a series of phases characterized by the movement of ions across the cardiac cell membranes, leading to the depolarization and repolarization of the cardiac myocytes.
Ionic Basis of Cardiac Action Potentials
2.6K
Structure of Cardiac Muscles01:13

Structure of Cardiac Muscles

14.2K
Cardiac muscle, or myocardium, is a specialized type of muscle found exclusively in the heart. Its unique structural and functional characteristics enable the heart to perform its vital role of pumping blood throughout the body continuously and rhythmically. The cardiac muscle cells, or cardiomyocytes, possess an endomysium and perimysium but do not have an epimysium.
Compared to skeletal muscles, cardiac muscle cells are small and mostly have a single nucleus. Additionally, they are usually...
14.2K
G-Protein Gated Ion Channels01:21

G-Protein Gated Ion Channels

4.8K
GPCRs are primarily responsible for our sense of smell, taste, and vision.  The binding of a sensory stimulus activates GPCR to stimulate effector proteins, many of which are ion channels in the sensory organs. GPCRs modulate the opening and closing of the target ion channels either directly by binding them, or by releasing second messengers that activate these channels. As ions move across the membrane, the membrane potential is altered, which induces an appropriate response.
Sensory...
4.8K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Collagen-Bearing Exosomes from Breast Cancer-Associated Fibroblasts Promote T-cell Dysfunction.

Cancer research communications·2026
Same author

Overcoming impaired antigen presentation in tumor-draining lymph nodes facilitates immunotherapy.

Journal for immunotherapy of cancer·2025
Same author

Inhibiting B cells enhances the efficacy of STING agonism or immune checkpoint blockade in hepatocellular carcinoma.

Nature communications·2025
Same author

Optimizing Cancer Vaccinations Using a Physiologically Based Pharmacokinetic (PBPK) Model.

bioRxiv : the preprint server for biology·2025
Same author

The anti-virus T cell response dominates the anti-cancer response in oncolytic virus therapy.

bioRxiv : the preprint server for biology·2025
Same author

Overcoming impaired antigen presentation in tumor draining lymph nodes facilitates immunotherapy.

bioRxiv : the preprint server for biology·2025
Same journal

Non-canonical amino acid incorporation enables minimally disruptive labeling of stress granule and TDP-43 proteinopathy.

eLife·2026
Same journal

Analysis of dendritic input currents during place field dynamics.

eLife·2026
Same journal

TopoMetry systematically learns and evaluates the latent geometry of single-cell data.

eLife·2026
Same journal

Navigating the path: Advice to physician-scientists on choosing a clinical specialty.

eLife·2026
Same journal

Neural activity profiles reveal overlapping, intermingled subpopulations spanning area borders in mouse sensorimotor cortex.

eLife·2026
Same journal

The exquisite mechanics of a tsetse bite.

eLife·2026
查看所有相关文章

相关实验视频

Updated: Sep 14, 2025

Generation of Murine Cardiac Pacemaker Cell Aggregates Based on ES-Cell-Programming in Combination with Myh6-Promoter-Selection
08:52

Generation of Murine Cardiac Pacemaker Cell Aggregates Based on ES-Cell-Programming in Combination with Myh6-Promoter-Selection

Published on: February 17, 2015

9.8K

接近心脏起器细胞.

Pin-Ji Lei1,2, Timothy P Padera1,2

  • 1Edwin L Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital Cancer Center, Massachusetts General Hospital, Boston, United States.

eLife
|July 22, 2025
PubMed
概括
此摘要是机器生成的。

淋巴肌细胞控制小鼠的淋巴血管收缩. 这一发现推动了我们对淋巴系统功能和流体运输的理解.

科学领域:

  • 生理学 生理学 生理学
  • 细胞生物学 细胞生物学
  • 血管生物学 血管生物学

背景情况:

  • 淋巴系统对于液体平衡和免疫监测至关重要.
  • 收集淋巴血管会出现自发收缩,驱动淋巴流动.
  • 调节淋巴血管收缩的细胞机制尚未完全理解.
关键词:
细胞生物学 细胞生物学细胞收缩 细胞收缩淋巴系统的淋巴系统.这里是鼠标鼠标鼠标鼠标鼠标鼠标.肌肉细胞 肌肉细胞肌肉细胞心脏起器细胞是一种细胞.

更多相关视频

Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation
08:56

Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation

Published on: September 24, 2021

2.8K
Electrophysiological Analysis of human Pluripotent Stem Cell-derived Cardiomyocytes hPSC-CMs Using Multi-electrode Arrays MEAs
11:13

Electrophysiological Analysis of human Pluripotent Stem Cell-derived Cardiomyocytes hPSC-CMs Using Multi-electrode Arrays MEAs

Published on: May 12, 2017

20.2K

相关实验视频

Last Updated: Sep 14, 2025

Generation of Murine Cardiac Pacemaker Cell Aggregates Based on ES-Cell-Programming in Combination with Myh6-Promoter-Selection
08:52

Generation of Murine Cardiac Pacemaker Cell Aggregates Based on ES-Cell-Programming in Combination with Myh6-Promoter-Selection

Published on: February 17, 2015

9.8K
Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation
08:56

Sterile Pericarditis in Aachener Minipigs As a Model for Atrial Myopathy and Atrial Fibrillation

Published on: September 24, 2021

2.8K
Electrophysiological Analysis of human Pluripotent Stem Cell-derived Cardiomyocytes hPSC-CMs Using Multi-electrode Arrays MEAs
11:13

Electrophysiological Analysis of human Pluripotent Stem Cell-derived Cardiomyocytes hPSC-CMs Using Multi-electrode Arrays MEAs

Published on: May 12, 2017

20.2K