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Updated: Sep 14, 2025

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
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α-醇重新排列,以获得四环天然产品

Alexandru Sara1, Ulrike Eggert1, Markus Kalesse1,2

  • 1Institute of Organic Chemistry, Gottfried Wilhelm Leibniz Universität Hannover, 30167 Hannover, Germany.

Organic letters
|July 22, 2025
PubMed
概括

这项研究引入了一种新方法来合成四环天然产品,这对于各种生物活动至关重要. 该协议可实现对关键分子结构的立体选择性合成和反转.

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