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慢性药物滥用对听觉和静脉系统的影响:初步发现

Amanda Chiao^1,2, Michelle L Hughes², Sarah Rogoz^2,3

¹Division of Otolaryngology Head & Neck Surgery, Department of Surgery, Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, Texas, USA.

Ear and hearing

|July 22, 2025

概括

慢性物质滥用会对听力和前庭功能产生负面影响,增加沟通障碍和成年人患有物质使用障碍 (SUD) 的跌倒风险. 需要进一步的研究来了解这些影响.

科学领域:

神经科学是一个神经科学.
耳鼻喉科耳鼻喉科耳鼻喉科
公共卫生公共卫生

背景情况:

药物使用障碍 (SUDs) 越来越多地与听觉和前体缺陷有关,但缺乏全面的研究.
现有的文献主要包括病例报告或小型研究,通常不评估听觉和前庭系统.
滥用物质对感官系统的耳毒和神经毒性影响需要进一步调查.

研究的目的:

调查慢性药物滥用对成年人听觉和前庭功能的影响.
为了比较具有滥用药物史 (SUD组) 个人与对照组的听觉和前庭结果.
为了确定药物滥用是否导致高频听力损失和中枢前庭异常.

主要方法:

分析了60名有滥用药物历史的成年人和20名对照人群的数据.
使用了一系列综合测试,包括认知查,听力测试 (标准和扩展高频),耳声发射,听觉脑干反应 (ABR),语音噪音测试,眼运动功能和前庭评估 (vHIT,VEMPs,平衡测试).
根据吸烟和噪音暴露等潜在的混因素进行调整.

主要成果:

与对照组相比,SUD组表现出较差的认知查得分和在标准和扩展的高频范围内显著较差的听觉值,即使在调整后.
听觉通路分析显示,在SUD组中,扭曲产品的耳声波排放和ABR波III和V的幅度较小,这表明耳功能障碍.
患有SUD的个体表现出异常眼运动功能的显著更高的比率和受损的双重姿态,表明中枢前庭系统和平衡障碍.

结论:

慢性物质滥用对成年人的听觉和前庭系统都有负面影响.
听觉发现表明耳起源而不是经典的耳毒性,而前庭结果与中央药物效应一致.
这些发现凸显了对SUD患者进行诊断监测的必要性,以解决潜在的通信障碍并降低跌倒风险.

关键词:

酒精饮料酒精饮料酒精饮料酒精饮料听力损失听力损失非法药物非法药物非法药物在阿片类药物中,阿片类药物耳部毒性耳部毒性使用物质使用物质.输入口损失输入口损失阴道中毒性阴道中毒性

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