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Updated: Sep 14, 2025

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
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乳腺活检和乳腺癌风险在以色列BRCA生殖系病原性变体携带者

Dana Madorsky Feldman1, Miri Sklair-Levy1,2,3, Yael Laitman4

  • 1Meirav High-Risk Clinic, Sheba Medical Center, Tel-Hashomer, Ramat Gan, Israel.

Breast cancer research and treatment
|July 22, 2025
PubMed
概括

对于BRCA1/2携带者,更多的乳腺活检和BRCA1致病变体 (PVs) 与更高的乳腺癌 (BC) 风险相关. 纤维腺瘤诊断似乎不会增加这个高风险组的BC风险.

关键词:
亚型性 亚型性 亚型性在BRCA光伏运营商.乳腺活检 乳腺活检乳腺癌是什么? 乳腺癌是什么组织学不稳定性 组织学不稳定增殖性和非增殖性良性乳腺疾病.

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Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
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