饮食障碍患者中处方药和非处方药的使用情况
Sarah-Catherine Rodan1,2,3, Sarah Maguire3,4, Noah Meez1
1Lambert Initiative for Cannabinoid Therapeutics, Brain and Mind Centre, The University of Sydney, Sydney, New South Wales, Australia.
JAMA network open
|July 22, 2025
概括
大麻和迷幻药可能有助于缓解饮食障碍症状,而处方抗抑郁药对一般心理健康更有益. 酒精,尼古丁和烟草被认为是最有害的.
科学领域:
- 精神病学是一个精神病学.
- 心理药理学 心理药理学
- 饮食障碍 饮食障碍 饮食障碍 饮食障碍
背景情况:
- 对于饮食障碍 (EDs) 存在很少有效的药物治疗方法.
- 患有ED的个体中高水平的物质使用表明潜在的自我治疗.
- 了解药物使用模式对于开发向治疗至关重要.
研究的目的:
- 探索ED患者在使用处方药和非处方药方面的经验.
- 评估各种物质对ED症状和整体心理健康的感知益处和危害.
主要方法:
- 全球在线调查 (MED-FED) 于2022年11月至2023年5月进行.
- 招募了自我报告ED或饮食失调的成年人.
- 评估最近使用处方药和非处方药的情况,对ED症状和心理健康的感知益处和危害进行评分.
主要成果:
- 超过5000名参与者完成了调查,其中大多数是女性,被诊断为神经性厌食症,神经性 булимия,过度饮食障碍或避免/限制性食物摄入障碍.
- 大麻和迷幻药在改善ED症状方面被评为最高.
- 处方抗抑郁药对一般心理健康有益,但对ED症状无益,除了治疗神经过敏症的fluoxetine和治疗过度饮食障碍的lisdexamfetamine. 酒精,尼古丁和烟草被认为是最有害的.
结论:
- 大麻和迷幻药在缓解ED症状方面显示出潜在的有效性,这需要进一步的研究.
- 处方精神药被认为对一般的心理健康比对特定的ED症状更有益.
- 这些发现突出了物质使用和饮食障碍之间的复杂关系,为未来的治疗策略提供了信息.
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