克服数字沟对老年成人中前额回膜缩的影响:大规模回顾性磁共振成像队列研究
Yumeng Li1,2, Xinyue Zhang1,2, Jiaqing Sun3
1State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, No.19, Xinjiekouwai Street, Haidian District, Beijing, 100875, China, 86 15810127521.
Journal of medical Internet research
|July 22, 2025
概括
克服数字沟 (DD) 的老年人显示出更好的大脑结构和更慢的认知衰老. 移动数字干预可能有助于预防老年人的认知衰退.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 认知科学 认知科学
- 信息技术 信息技术 信息技术
背景情况:
- 数字沟 (DD) 不成比例地影响着老年人,为技术采用创造了障碍.
- 虽然技术使用与认知益处有关,但DD的长期神经结构和认知影响尚不清楚.
研究的目的:
- 通过大规模的神经成像数据,研究数字沟 (DD) 对老年人大脑结构和认知衰老的长期影响.
- 为了比较DD参与和没有DD参与的老年人之间的结构和认知差异.
- 检查DD暴露对神经基质和认知功能的纵向影响.
主要方法:
- 1280名老年人 (65-90岁) 接受了认知评估和结构性MRI扫描.
- 倾向性得分匹配创建了DD (n=640) 和克服DD (n=640) 参与者的匹配组.
- 使用搜索灯分析和交叉验证的计算框架评估了大脑结构和认知表征的群体差异,包括纵向衰老率.
主要成果:
- 与克服DD组相比,DD组在执行功能和处理速度方面表现出显著的缺陷.
- 在DD组中观察到灰质体积减少,包括海马体和状环在内的区域.
- 纵向分析显示,DD组中部额叶回路的灰质下降速度更快,介导了情节性记忆的下降.
结论:
- 克服数字沟的老年人保持了更好的灰质结构,并经历了较慢的认知衰退,特别是在前部区域.
- 研究结果表明,移动数字干预可能是预防老年人认知能力下降的策略.
相关概念视频
Cognitive Development During Adulthood
288
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
288
The Effect of Aging on Tissues
2.5K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
2.5K


