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Updated: Sep 14, 2025

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与GLP-1RA相关的糖尿病脊椎骨干复合和常见的支柱状神经病变:病例对照评估

James D Triplett1,2, Marcus V Pinto1, Nathan P Young1

  • 1Department of Neurology, Mayo Clinic, Rochester, MN.

Neurology
|July 22, 2025
PubMed
概括

类似葡萄糖-1受体激动剂 (GLP-1RAs) 与糖尿病腰部神经复合神经病变 (DLRPN) 和常见支柱状神经病变 (CFN) 的风险增加有关. 这些神经病变似乎与使用GLP-1RAs的患者经历的显著代谢变化和体重减轻有关.

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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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