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Updated: Jun 12, 2026

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使用深度学习算法分析结肠直肠癌患者的原发性和同步性肝转移之间的瘤微环境特征

Oluwadunni E Emiloju1, Nathan R Foster2, Bahar Saberzadeh Ardestani3

  • 1Department of Oncology, Mayo Clinic, Rochester, MN.

JCO clinical cancer informatics
|July 22, 2025
PubMed
概括

结肠直肠肝转移 (CRLM) 与初级结肠直肠瘤 (CRC) 相比,表现出更具侵略性的特征,如较高的瘤-瘤比率 (TSR) 和亡. 这些发现突出了转移性疾病中独特的微环境特征.

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The Tumor Microenvironment02:17

The Tumor Microenvironment

Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...