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Updated: Sep 14, 2025

PIP-on-a-chip: A Label-free Study of Protein-phosphoinositide Interactions
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蛋白质的识别和组装由一个Phosphocavitand.

Colin P Wren1, Ronan J Flood1, Niamh M Mockler1

  • 1School of Biological and Chemical Sciences, University of Galway, Galway H91 TK33, Ireland.

Journal of the American Chemical Society
|July 22, 2025
PubMed
概括

一种含酸盐的新型宏循环,phosphocavitand (pctx),通过选择性结合N端残留物和氨酸,使受控的蛋白质组装成为可能. 这一发现为蛋白质晶体工程和生物材料制造开辟了新的途径.

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