在手术后的妇科瘤患者中持续使用阿片类药物
Michaela Pesce1, Katelyn Tondo-Steele1, Cynthia Stroup1
1University of Michigan, Department of Obstetrics and Gynecology, 1500 E. Medical Center Dr., Ann Arbor, MI 48109, USA.
Gynecologic oncology
|July 22, 2025
概括
在妇科瘤手术后持续使用阿片类药物在30天和90天是低的. 手术前的焦虑,抑郁,慢性疼痛或物质使用并没有预测持续的阿片类药物使用,但术后的并发症确实如此.
科学领域:
- 在瘤学瘤学.
- 疼痛管理 疼痛管理
- 药理学 药理学是指药理学的学科.
背景情况:
- 手术后使用阿片类药物是一个问题,特别是在妇科瘤学中.
- 确定持续使用阿片类药物的预测因素对于优化疼痛管理策略至关重要.
研究的目的:
- 确定因妇科恶性瘤而接受手术的患者在术后30天和90天持续使用阿片类药物的比率.
- 确定患者的特征,包括精神健康史和物质使用,这些特征预测了持续的阿片类药物使用.
主要方法:
- 一个问卷评估了手术后30天的阿片类药物使用模式,通过图表审查验证了答案.
- 倾向性得分匹配比较了30天阿片类药物使用和不使用的患者,以确定风险因素.
- 分析了患者的焦虑,抑郁,慢性疼痛,药物使用和术后并发症的病史.
主要成果:
- 在431名未使用过阿片类药物的患者中,2.8%在30天后使用阿片类药物,在术后90天后使用了0.5%.
- 根据焦虑,抑郁,慢性疼痛或物质使用史,没有发现持续使用阿片类药物的显著差异.
- 患有术后并发症的患者在30天后更有可能使用阿片类药物 (33.3%) 与没有 (8.3%) 的患者相比.
结论:
- 在妇科瘤病患者中,术后持续使用阿片类药物的比例较低.
- 焦虑,抑郁,慢性疼痛或药物使用史并没有预测持续使用阿片类药物.
- 手术后并发症可能会增加持续使用阿片类药物的风险,为处方策略提供信息.
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