相关实验视频
Updated: Sep 14, 2025
08:49
Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
16.6K
临近结肠内镜粘膜切除后预防性剪切对延迟出血的影响:多中心随机对照试验 (CLIPPER)
Gijs Kemper1, Ayla S Turan1, Ramon-Michel Schreuder2
1Department of Gastroenterology and Hepatology, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, Netherlands.
Endoscopy
|July 22, 2025
概括
在内镜粘膜切除 (EMR) 后,针对大近接结肠聚体的预防性剪切在一项大型临床实践研究中没有减少延迟出血. 这一发现与一些大型中心试验形成鲜明对比,这表明当前的实践可能不会从这种干预中受益.
科学领域:
- 胃肠病学 胃肠病学
- 内視鏡外科手術 內視鏡外科手術
- 结肠直肠癌 预防 预防
背景情况:
- 延迟出血是大结直肠多体内膜切除 (EMR) 后的常见并发症.
- 之前在高人数中心的研究表明,预防性剪切可能会降低这种风险.
- 预防性剪切在常规临床实践中对于特定的多类型的有效性仍然不清楚.
研究的目的:
- 在日常临床实践中评估预防性剪切在减少EMR后延迟出血的作用,用于大,近端,非踏脚的息肉.
主要方法:
- 在荷兰的19个医院进行了一项随机对照试验.
- 接受EMR的大型 (≥20毫米),近端,横向扩散或状息肉的患者被随机分配 (1:1) 接受或不接受预防性剪切.
- 主要终点是延迟出血,根据治疗意图进行分析.
主要成果:
- 356名患者被随机分配;177人接受了预防性剪切,179人没有.
- 延迟出血发生在预防性剪切组的9.0%,对照组的6.1% (P=0.30).
- 没有报告与治疗相关的死亡.
结论:
- 在现实临床环境中,预防性剪切并没有显著降低对接受EMR的大型,近端,横向扩散和静止性息肉的患者的延迟出血.
- 这些发现表明,在标准实践中,常规预防性剪切可能对这种患者群体没有好处.
相关概念视频
01:25Endoscopic Procedures II: Colonoscopy
192
The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
192
01:26Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
177
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
177
01:21Inflammatory Bowel Disease V: Surgical Management
219
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
219