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Updated: Sep 14, 2025

Three-Dimensional Bone Extracellular Matrix Model for Osteosarcoma
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异常的EZHIP表达驱动骨髓肉瘤中的瘤发生

Wajih Jawhar1,2,3, Geoffroy Danieau2,4, Alva Annett5,6

  • 1Division of Experimental Medicine, Department of Medicine, McGill University, Montreal, Quebec, Canada.

Nature communications
|July 22, 2025
PubMed
概括

EZHIP是一种模仿胆固醇蛋白的蛋白质,经常在骨髓瘤 (OS) 中发现. 它的表达预测治疗反应不佳,并通过改变表观遗传标记和阻碍细胞分化来驱动瘤的攻击性.

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