腹腔透析后瘦组织质量的早期变化:患病率,危险因素和临床影响
Lixing Xu1,2, Jack Kit-Chung Ng1,2, Gordon Chun-Kau Chan1
1Carol & Richard Yu Peritoneal Dialysis Research Centre, Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
BMC nephrology
|July 22, 2025
概括
腹腔透析 (PD) 患者的早期肌肉损失很常见,随着脂肪组织质量 (ATM) 的增加,瘦组织质量 (LTM) 减少. 然而,这些最初的身体组成变化似乎没有影响患者的存活率.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 临床营养学 临床营养学
- 身体组成分析 身体成分分析
背景情况:
- 肌肉消耗与腹腔透析 (PD) 患者的不良结果有关.
- 在PD开始后肌肉质量的早期变化及其临床影响尚不清楚.
- 这项研究调查了影响六个月内新患病患者瘦组织质量 (LTM) 变化的因素.
研究的目的:
- 在新的PD患者中,确定影响六个月内LTM变化的因素.
- 评估早期LTM变化对临床结果的预后意义.
- 分析LTM和脂肪组织质量 (ATM) 变化之间的关系.
主要方法:
- 该研究包括90名新的PD患者.
- 生物阻抗谱法用于测量六个月内的LTM和ATM变化.
- 作为结果指标,记录了患者和技术生存率.
主要成果:
- 在PD六个月后,体重和BMI保持稳定.
- 46.7%的患者在LTM下降≥1公斤.
- LTM的百分比下降了 (63.4%至61.5%),而ATM则增加,LTM和ATM变化之间存在显著的反相关性 (p < 0.0001).
结论:
- 在PD的前六个月内,LTM减少和ATM增加的趋势发生在PD的前六个月内,尽管体重稳定.
- 这些早期的身体组成变化与不良的患者或技术存活率无关.
相关概念视频
Peritoneal Dialysis III: Nursing Management
149
Peritoneal dialysis, or PD, utilizes the peritoneal membrane as a filter to eliminate excess fluid and waste products. Effective nursing management is essential for ensuring patient safety, preventing complications, and promoting optimal function of the peritoneal dialysis process.Assessment and MonitoringNurses must thoroughly assess the patient before, during, and after each dialysis session. Regular monitoring includes vital signs, daily weight, fluid intake and output, and laboratory values...
149
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
110
Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
110
Hemodialysis III: Nursing Management
194
The nursing management of a patient undergoing hemodialysis includes several critical steps, starting with a thorough assessment before the procedure.Before the Hemodialysis ProcedureFirst, record the patient's vital signs—blood pressure, heart rate, respiratory rate, and temperature—to establish a baseline. This baseline is essential for detecting conditions such as hypotension that could impact the patient's response to dialysis. Document the patient's pre-dialysis weight, as this...
194
Peritoneal Dialysis I: Introduction and Procedure
216
Peritoneal dialysis (PD) is a procedure that facilitates the exchange of solutes, waste products, electrolytes, and excess fluid between the blood in the peritoneal capillaries and a dialysis solution introduced into the peritoneal cavity.Principles of Peritoneal Dialysis (PD)Diffusion: Waste products such as urea and electrolytes move from high concentrations in the blood to low concentrations in the dialysate across the peritoneal membrane. This mechanism is driven by the concentration...
216
Chronic Kidney Disease III: Interprofessional Care
80
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
80
Acute Kidney Injury V: Interprofessional Care
46
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
46


